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ASP7663

品牌
Sigma-Aldrich
CAS
1190217-35-6
货号
SML1467
规格纯度
≥98% (HPLC)
参考价格
1260.64 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
1190217-35-6
ASP7663
(E)-[7-Fluoro-1-(2-methylpropyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]acetic acid
(2E)-2-[7-Fluoro-1,2-dihydro-1-(2-methylpropyl)-2-oxo-3H-indol-3-ylidene]acetic acid
产品介绍:

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

ASP7663 is a selective activator of transient receptor potential ankyrin 1 (TRPA1), known to play a role for chemical sensing in the pain pathway. ASP7663 activated human, rat, and mouse TRPA1 receptors with EC50 values of 510, 540, and 500 nM, respectively, and little or no affinity at more than 60 other related receptors, channels and enzymes. ASP7663 enhanced colonic motility and exerted analgesic effects against abdominal pain in mouse models.

基本信息

经验(实验)分子式C14H14FNO3
分子量263.26
PubChem化学物质编号329825901
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色light orange to dark orange
溶解性DMSO: 25 mg/mL, clear
储存温度2-8℃
SMILES stringCC(C)CN(C1=C(F)C=CC=C1/C2=C\C(O)=O)C2=O
InChI1S/C14H14FNO3/c1-8(2)7-16-13-9(4-3-5-11(13)15)10(14(16)19)6-12(17)18/h3-6,8H,7H2,1-2H3,(H,17,18)/b10-6+
InChI keyRCVZUIGCNAAMIC-UXBLZVDNSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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