产品说明
生化/生理作用
APC366 is a selective inhibitor of mast cell tryptase, which is involved with allergenic response. It thereby also inhibits protease-activated receptor PAR2, a G-protein-coupled receptor that is activated by mast cell tryptase. Tryptase has been proposed to be involved in fibrosis, joint inflammation and also in promoting breast cancer angiogenesis, all of which APC366 inhibited.
基本信息
| 经验(实验)分子式 | C22H28N6O4 · xC2HF3O2 |
| 分子量 | 440.50 (free base basis) |
产品性质
| 测定 | ≥97% (HPLC) |
| 形式 | lyophilized powder |
| 颜色 | white to off-white |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| SMILES string | FC(F)(C(O)=O)F.NC(NCCC[C@@H](C(N1CCC[C@H]1C(N)=O)=O)NC(C2=C(O)C3=CC=CC=C3C=C2)=O)=N |
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