产品说明
生化/生理作用
AQ1, an anthraquinone derivative, is a potent stabilizer of c-KIT G-quadruplexes (G4) that downregulates c-KIT mRNA and protein expression in human and canine cell lines. Also, AQ1 causes inhibition BCL2 gene expression in HGC27 and MCF7 cells. AQ1 inhibits proliferation of in varies human tumor cell lines including HCG27, MCF7 and imatinib resistant HMC1.2 cells.
基本信息
| 经验(实验)分子式 | C32H44N8O6 · xC2HF3O2 |
| 分子量 | 636.74 (free base basis) |
产品性质
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | faint yellow to dark orange |
| 溶解性 | H2O: 2 mg/mL, clear |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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