产品说明
应用
BAY 41-2272 has been used for the stimulation of guanylate cyclase in heart and neurons.
包装
5, 25 mg in glass bottle
生化/生理作用
BAY 41-2272 is an activator of soluble guanylate cyclase at a novel, NO-independent regulatory site. BAY 41-2272 is the first product that stimulates sGC through a non-NO mechanism. BAY 41-2272 inhibits platelet aggregation and induces vasorelaxation without nitrate tolerance.
特点和优势
This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
基本信息
| 经验(实验)分子式 | C20H17FN6 |
| 分子量 | 360.39 |
| MDL编号 | MFCD06411391 |
| PubChem化学物质编号 | 24892096 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥97% (HPLC) |
| 形式 | powder |
| 颜色 | white to light brown |
| mp | 210.5-211.4 ℃ |
| 溶解性 | DMSO: 5 mg/mL, clear (warmed) |
| 创始人 | Bayer |
| 储存温度 | 2-8℃ |
| SMILES string | Nc1nc(ncc1C2CC2)-c3nn(Cc4ccccc4F)c5ncccc35 |
| InChI | 1S/C20H17FN6/c21-16-6-2-1-4-13(16)11-27-20-14(5-3-9-23-20)17(26-27)19-24-10-15(12-7-8-12)18(22)25-19/h1-6,9-10,12H,7-8,11H2,(H2,22,24,25) |
| InChI key | ATOAHNRJAXSBOR-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
m.cnreagent.com
