CASIN

产品名称：

425399-05-9
CASIN
2-[(2,3,4,9-Tetrahydro-6-phenyl-1H-carbazol-1-yl)amino]ethanol
Cdc42 Activity-Specific Inhibitor

产品介绍：

产品说明

应用

CASIN has been used as a cell division control protein 42 homolog (Cdc42) inhibitor:

to study its effects on the stimulation of extracellular vesicles (EVs) in intestinal epithelial cells
to study its effects on mice jejunum
to study its effects on microbial adhesion-triggered endocytosis (MATE) vesicle morphology in segmented filamentous bacteria (SFB)-colonized mice

包装

5, 25 mg in glass bottle

生化/生理作用

CASIN is an inhibitor of Cdc42 GTPase, a small GTPase of the Rho-subfamily that plays important roles in cytoskeleton organization, cell cycle progression, signal transduction, and vesicle trafficking. CASIN generated a rejuvenated phenotype of Hematopoietic stem cells (HSCs), reversing the aging-related and polarity phenotype of aged HSCs to that of young HSCs in vivo..

基本信息

经验(实验)分子式	C₂₀H₂₂N₂O
分子量	306.40
MDL编号	MFCD01853271
PubChem化学物质编号	329825745

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	, white to very dark brown
溶解性	DMSO: 20 mg/mL, clear
储存温度	2-8℃
SMILES string	OCCNC1CCCC2=C1NC3=C2C=C(C4=CC=CC=C4)C=C3
InChI	1S/C20H22N2O/c23-12-11-21-19-8-4-7-16-17-13-15(14-5-2-1-3-6-14)9-10-18(17)22-20(16)19/h1-3,5-6,9-10,13,19,21-23H,4,7-8,11-12H2
InChI key	RXIUMAOXORBRCY-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable