CBLC000 trifluoroacetate

产品名称：

324780-02-1
CBLC000 trifluoroacetate
N,N-Diethyl-3,6-dinitro-9H-carbazole-9-ethanamine trifluoroacetate
9H-Carbazole-9-ethanamine, N,N-diethyl-3,6-dinitro- trifluoroacetate
Curaxin CBLC000 trifluoroacetate

产品介绍：

产品说明

生化/生理作用

CBLC000 is a potent inhibitor of FACT (facilitates chromatin transcription) complex that activates p53 and suppresses NF-kB without genotoxicity. CBLC000 induces chromatin trapping of FACT both in vitro and in vivo. CBLC000 exhibits brad anticancer activity. CBLC000 analog clinical candidate CBL0137 decreases self-renewal of GBM stem cells (GSC).

基本信息

经验(实验)分子式	C₁₈H₂₀N₄O₄ · C₂HF₃O₂
分子量	470.40
NACRES	NA.77

产品性质

测定	≥95% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
储存温度	2-8℃
SMILES string	CCN(CC)CCN1C2=C(C=C([N+]([O-])=O)C=C2)C3=C1C=CC([N+]([O-])=O)=C3.FC(F)(C(O)=O)F

安全信息

象形图
警示用语：	Warning
危险声明	H302 - H315 - H413
预防措施声明	P273 - P301 + P312 + P330 - P302 + P352
危险分类	Acute Tox. 4 Oral - Aquatic Chronic 4 - Skin Irrit. 2
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable