产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
CCT036477 is an inhibitor of Wnt signaling. It does not alter β-catenin levels but blocks transcription at the β-catenin level. CCT036477 inhibited growth in several cancer cell lines and showed clear activity in vivo, blocking development of Zebrafish and Xenopus embryos and expression of Wnt target genes.
基本信息
经验(实验)分子式 | C21H18ClN3 |
分子量 | 347.84 |
MDL编号 | MFCD01831143 |
PubChem化学物质编号 | 329825199 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | white to tan |
溶解性 | DMSO: ≥20 mg/mL (warm to 60℃) |
储存温度 | −20℃ |
SMILES string | Cc1[nH]c2ccccc2c1C(Nc3ccccn3)c4ccc(Cl)cc4 |
InChI | 1S/C21H18ClN3/c1-14-20(17-6-2-3-7-18(17)24-14)21(15-9-11-16(22)12-10-15)25-19-8-4-5-13-23-19/h2-13,21,24H,1H3,(H,23,25) |
InChI key | IFOHRIXRQPOHQZ-UHFFFAOYSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |