ER-27319

产品名称：

201010-95-9
ER-27319
10-(3-Aminopropyl)-3,4-dimethyl-9-acridone oxalate

产品介绍：

产品说明

包装

5 mg in glass bottle
25 mg in poly bottle

生化/生理作用

ER-27319 inhibits Syk activation with an IC₅₀ = 10 μM. ER-27319 inhibits Syk by preventing the phosphorylated ITAM domain of FcεRI γ from activating Syk. ER-27319 does NOT inhibit previously activated Syk.
Selective Syk inhibitor. Induces tyrosine phosphorylation of Syk that has been demonstrated as critical for degranulation.

特点和优势

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

基本信息

经验(实验)分子式	C₂₀H₂₂N₂O₅
分子量	370.40
MDL编号	MFCD07784502
PubChem化学物质编号	24724472
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	solid
溶解性	DMSO: 28 mg/mL
储存温度	2-8℃
SMILES string	OC(=O)C(O)=O.Cc1ccc2C(=O)c3ccccc3N(CCCN)c2c1C
InChI	1S/C18H20N2O.C2H2O4/c1-12-8-9-15-17(13(12)2)20(11-5-10-19)16-7-4-3-6-14(16)18(15)21;3-1(4)2(5)6/h3-4,6-9H,5,10-11,19H2,1-2H3;(H,3,4)(H,5,6)
InChI key	IIELZHYJYZBSGG-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302 + H312
预防措施声明	P264 - P270 - P280 - P301 + P312 - P302 + P352 + P312 - P362 + P364
危险分类	Acute Tox. 4 Dermal - Acute Tox. 4 Oral
储存分类代码	11 - Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable