产品说明
应用
Eupatilin has been used to investigate its inhibitory effects on intracranial hemorrhage (ICH)-induced inflammation and its anti-inflammatory mechanisms in mouse BV2 cells, in vitro. It has also been used as a standard for its quantitative estimation in Artemisia extracts by microcolumn high performance liquid chromatography with diode array (HPLC-DAD) assay.
包装
5, 25 mg in glass bottle
生化/生理作用
Eupatilin is an important constituent in the leaves of Artemisia argyi and also an active component of DA-9601. It exhibits anti-apoptotic effects. Eupatilin provides protection against tumor necrosis factor α (TNF-α)-mediated inflammation in human umbilical vein endothelial cells. It is used in the treatment of gastritis and peptic ulcers. Eupatilin safeguards gastric epithelial cells from oxidative damage and smooth muscle cells from indomethacin-induced cell damage. Eupatilin lowers bile acid-stimulated hepatocyte apoptosis.
Eupatilin is a flavone with anti-oxidative, anti-inflammatory, and anti-cancer properties.
基本信息
| 经验(实验)分子式 | C18H16O7 |
| 分子量 | 344.32 |
| MDL编号 | MFCD13194819 |
| PubChem化学物质编号 | 329826018 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 生物来源 | (Isolated from Artemisia sp.) |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 储存条件 | desiccated protect from light |
| 颜色 | white to beige |
| 溶解性 | DMSO: 20 mg/mL, clear |
| 储存温度 | −20℃ |
| SMILES string | O=C1C=C(C2=CC=C(OC)C(OC)=C2)OC3=CC(O)=C(OC)C(O)=C31 |
| InChI | 1S/C18H16O7/c1-22-12-5-4-9(6-14(12)23-2)13-7-10(19)16-15(25-13)8-11(20)18(24-3)17(16)21/h4-8,20-21H,1-3H3 |
| InChI key | DRRWBCNQOKKKOL-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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