2′,4,4′-Trihydroxy-3′-(3-methyl-2-butenyl)-chalcone

产品名称：

20784-50-3
Isobavachalcone
Corylifolinin
Isobacachalcone
(2E)-1-[2,4-Dihydroxy-3-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one
2′,4,4′-Trihydroxy-3′-(3-methyl-2-butenyl)-chalcone

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Isobavachalcone is a chalcone isolated from multipurpose medical plant Psoralea corylifolia that inhibits LPS-induced ICAM-1 expression and leukocyte adhesion to brain endothelial cells. It appears that isobavachalcone modulates both MyD88-dependent and TRIF-dependent signaling of toll-like receptor 4 (TLR4). Isobavachalcone significantly inhibits both oligomerization and fibrillization of Aβ42. Isobavachalcone exhibits a wide spectrum of biological activities including antioxidative, antiplatelet, antimicrobial, anti-inflammatory, antitumor, and neuroprotective.

基本信息

经验(实验)分子式	C₂₀H₂₀O₄
分子量	324.37
MDL编号	MFCD00902090
PubChem化学物质编号	329825889
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPCE)
形式	powder
储存条件	desiccated protect from light
颜色	white to beige
溶解性	DMSO: 5 mg/mL, clear (warmed)
储存温度	−20℃
SMILES string	OC1=C(CC=C(C)C)C(O)=C(C(/C=C/C2=CC=C(O)C=C2)=O)C=C1
InChI	1S/C20H20O4/c1-13(2)3-9-16-19(23)12-10-17(20(16)24)18(22)11-6-14-4-7-15(21)8-5-14/h3-8,10-12,21,23-24H,9H2,1-2H3/b11-6+
InChI key	DUWPGRAKHMEPCM-IZZDOVSWSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable