产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
Isobavachalcone is a chalcone isolated from multipurpose medical plant Psoralea corylifolia that inhibits LPS-induced ICAM-1 expression and leukocyte adhesion to brain endothelial cells. It appears that isobavachalcone modulates both MyD88-dependent and TRIF-dependent signaling of toll-like receptor 4 (TLR4). Isobavachalcone significantly inhibits both oligomerization and fibrillization of Aβ42. Isobavachalcone exhibits a wide spectrum of biological activities including antioxidative, antiplatelet, antimicrobial, anti-inflammatory, antitumor, and neuroprotective.
基本信息
经验(实验)分子式 | C20H20O4 |
分子量 | 324.37 |
MDL编号 | MFCD00902090 |
PubChem化学物质编号 | 329825889 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPCE) |
形式 | powder |
储存条件 | desiccated protect from light |
颜色 | white to beige |
溶解性 | DMSO: 5 mg/mL, clear (warmed) |
储存温度 | −20℃ |
SMILES string | OC1=C(CC=C(C)C)C(O)=C(C(/C=C/C2=CC=C(O)C=C2)=O)C=C1 |
InChI | 1S/C20H20O4/c1-13(2)3-9-16-19(23)12-10-17(20(16)24)18(22)11-6-14-4-7-15(21)8-5-14/h3-8,10-12,21,23-24H,9H2,1-2H3/b11-6+ |
InChI key | DUWPGRAKHMEPCM-IZZDOVSWSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich