JM6

产品名称：

1008119-83-2
JM6
3,4-Dimethoxy-N-[4-(3-nitrophenyl)-5-(1-piperidinylmethyl)-2-thiazolyl]-benzenesulfonamide
2-(3,4-Dimethoxybenzenesulfonylamino)-4-(3-nitrophenyl)-5-(piperidin-1-yl)methylthiazole

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

JM6 is a prodrug inhibitor of kynurenine 3-monooxygenase (KMO) that increases kynurenic acid levels and reduces extracellular glutamate in the brain. JM6 prevents spatial memory deficits, anxiety-related behavior, and synaptic loss in mouse model of Alzheimer disease.

特点和优势

This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式	C₂₃H₂₆N₄O₆S₂
分子量	518.61
MDL编号	MFCD22380618
PubChem化学物质编号	329825529
NACRES	NA.77

产品性质

质量水平	100
测定	≥97% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 2 mg/mL (clear solution, warmed)
储存温度	2-8℃
SMILES string	COc1ccc(cc1OC)S(=O)(=O)Nc2nc(c(CN3CCCCC3)s2)-c4cccc(c4)[N+]([O-])=O
InChI	1S/C23H26N4O6S2/c1-32-19-10-9-18(14-20(19)33-2)35(30,31)25-23-24-22(16-7-6-8-17(13-16)27(28)29)21(34-23)15-26-11-4-3-5-12-26/h6-10,13-14H,3-5,11-12,15H2,1-2H3,(H,24,25)
InChI key	AOZLMMDVJOGGEQ-UHFFFAOYSA-N

安全信息

储存分类代码	6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable