Mephetyl tetrazole

产品名称：

916923-10-9
Mephetyl tetrazole
1-[2-(4-Methoxyphenyl)ethyl]-5-(1-p-tolylcyclopropyl)-1H-tetrazole

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Mephetyl tetrazole is a potent and selective Kv1.5 potassium channel blocker. IC₅₀ = 330 nM; shows selective atrial prolongation (40%) of effective refractory period (ERP), but no effect on ventricular ERP Kv1.5 channel is a molecular target for the treatment of atrial fibrillation.

特点和优势

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式	C₂₀H₂₂N₄O
分子量	334.41
MDL编号	MFCD11045297
PubChem化学物质编号	329818044
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	oil
颜色	pale yellow
溶解性	DMSO: >5 mg/mL
储存温度	2-8℃
SMILES string	COc1ccc(CCn2nnnc2C3(CC3)c4ccc(C)cc4)cc1
InChI	1S/C20H22N4O/c1-15-3-7-17(8-4-15)20(12-13-20)19-21-22-23-24(19)14-11-16-5-9-18(25-2)10-6-16/h3-10H,11-14H2,1-2H3
InChI key	VREPWWBWXVLSEF-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)