K 858

产品名称：

72926-24-0
K 858
N-(4-Acetyl-4,5-dihydro-5-methyl-5-phenyl-1,3,4-thiadia zol-2-yl)acetamide
K858

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

Eg5 is a key protein involved in the formation of bipolar spindles. K858 is a selective ATP-uncompetitive mitotic kinesin Eg5 inhibitor. The compound induces mitotic arrest, caspase-3 activation and cell growth inhibition in HCT116 cells.

基本信息

经验(实验)分子式	C₁₃H₁₅N₃O₂S
分子量	277.34
MDL编号	MFCD00181155
PubChem化学物质编号	329817139
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to off-white
溶解性	DMSO: ≥20 mg/mL
储存温度	2-8℃
SMILES string	CC(=O)NC1=NN(C(C)=O)C(C)(S1)c2ccccc2
InChI	1S/C13H15N3O2S/c1-9(17)14-12-15-16(10(2)18)13(3,19-12)11-7-5-4-6-8-11/h4-8H,1-3H3,(H,14,15,17)
InChI key	JEFVYQYZCAVNTP-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302
危险分类	Acute Tox. 4 Oral
储存分类代码	11 - Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable