产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
Eg5 is a key protein involved in the formation of bipolar spindles. K858 is a selective ATP-uncompetitive mitotic kinesin Eg5 inhibitor. The compound induces mitotic arrest, caspase-3 activation and cell growth inhibition in HCT116 cells.
基本信息
| 经验(实验)分子式 | C13H15N3O2S |
| 分子量 | 277.34 |
| MDL编号 | MFCD00181155 |
| PubChem化学物质编号 | 329817139 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | white to off-white |
| 溶解性 | DMSO: ≥20 mg/mL |
| 储存温度 | 2-8℃ |
| SMILES string | CC(=O)NC1=NN(C(C)=O)C(C)(S1)c2ccccc2 |
| InChI | 1S/C13H15N3O2S/c1-9(17)14-12-15-16(10(2)18)13(3,19-12)11-7-5-4-6-8-11/h4-8H,1-3H3,(H,14,15,17) |
| InChI key | JEFVYQYZCAVNTP-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H302 |
| 危险分类 | Acute Tox. 4 Oral |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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