Pitavastatin calcium

产品名称：

147526-32-7
Pitavastatin calcium
(3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid calcium salt
(+)monocalcium bis{(3R, 5S, 6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-3,5dihydroxy-6-heptenoate}

产品介绍：

产品说明

生化/生理作用

Pitavastatin calcium is a water-soluble inhibitor of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Pitavastatin calcium is antilipemic and is used to reduce plasma cholesterol levels and prevent cardiovascular disease.

基本信息

经验(实验)分子式	C₂₅H₂₃FNO₄ · 0.5Ca
分子量	440.49

产品性质

测定	≥98% (HPLC)
形式	powder
旋光性	[α]/D +19 to +24°, c = 1 in acetonitrile: water (1:1)
储存条件	desiccated
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
储存温度	2-8℃
InChI	1S/2C25H24FNO4.Ca/c226-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-18(28)13-19(29)14-23(30)31;/h21-4,7-12,16,18-19,28-29H,5-6,13-14H2,(H,30,31);/q;;+2/p-2/b212-11+;/t218-,19-;/m11./s1
InChI key	RHGYHLPFVJEAOC-FFNUKLMVSA-L

安全信息

象形图
警示用语：	Warning
危险声明	H361f
预防措施声明	P201 - P308 + P313
危险分类	Repr. 2
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable