PRT4165

产品名称：

31083-55-3
PRT4165
2-(3-Pyridinylmethylene)-1H-indene-1,3(2H)-dione; 2-(3-Pyridylmethylene)-1,3-indandione
NSC 600157

产品介绍：

产品说明

生化/生理作用

PRT4165 is a potent inhibitor of PRC1 (polycomb-repressive complex 1)-mediated histone H2A ubiquitylation in vivo and in vitro. PRT4165 inhibits the in vitro histone H2A E3 ubiquitin ligase activity of PRC1 components RING1, RNF2, and a BMI1/RNF2 complex. PRT4165 also inhibits DNA double-strand breaks induced ubiquitylation of histone H2AX.

特点和优势

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基本信息

经验(实验)分子式	C₁₅H₉NO₂
分子量	235.24
MDL编号	MFCD00435709
PubChem化学物质编号	329825631

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 20 mg/mL, clear
储存温度	2-8℃
SMILES string	O=C1C(C(C2=C1C=CC=C2)=O)=CC3=CN=CC=C3
InChI	1S/C15H9NO2/c17-14-11-5-1-2-6-12(11)15(18)13(14)8-10-4-3-7-16-9-10/h1-9H
InChI key	OMHZFEWYVFWVLI-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable