Sal003

产品名称：

1164470-53-4
Sal003
(2E)-3-Phenyl-N-[2,2,2-trichloro-1-[[[(4-chlorophenyl)amino]thioxomethyl]amino]ethyl]-2-propenamide
3-Phenyl-N-(2,2,2-trichloro-1-((((4-chlorophenyl)amino)carbonothioyl)amino)ethyl)acrylamide

产品介绍：

产品说明

应用

Sal003 was used to study the role of eIF2α in Subtilase cytotoxin-induced apoptosis in HeLa cells.

包装

5, 25 mg in glass bottle

生化/生理作用

Sal003 inhibits the late long-term potentiation (L-LTP) and long-term memory formation in mammalian hippocampal slices. The effect of Sal003 on L-LTP is mediated by the transcription factor, ATF4.
Sal003 is a potent and cell-permeable eIF-2a phosphatase inhibitor.

基本信息

经验(实验)分子式	C₁₈H₁₅Cl₄N₃OS
分子量	463.21
MDL编号	MFCD00361095
PubChem化学物质编号	329824543

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
储存条件	desiccated protect from light
颜色	white to off-white
溶解性	DMSO: ≥10 mg/mL
相容性	for use with Bio-Rad CFX96
储存温度	2-8℃
SMILES string	Clc1ccc(NC(=S)NC(NC(=O)\C=C\c2ccccc2)C(Cl)(Cl)Cl)cc1
InChI	1S/C18H15Cl4N3OS/c19-13-7-9-14(10-8-13)23-17(27)25-16(18(20,21)22)24-15(26)11-6-12-4-2-1-3-5-12/h1-11,16H,(H,24,26)(H2,23,25,27)/b11-6+
InChI key	TVNBASWNLOIQML-IZZDOVSWSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H410
预防措施声明	P273 - P501
危险分类	Aquatic Acute 1 - Aquatic Chronic 1
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable