PS48

产品名称：

1180676-32-7
PS48
5-(4-Chloro-phenyl)-3-phenyl-pent-2-enoic acid

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

PS48 is a PDK1 (phosphoinositide-dependent protein kinase 1) activator which binds to the HM/PIF binding pocket rather than the ATP-binding site. PS48 is one of only a few truly allosteric compounds targeting a regulatory binding site on a protein kinase catalytic domain that is not adjacent to or overlapping with the ATP-binding site.

基本信息

经验(实验)分子式	C₁₇H₁₅ClO₂
分子量	286.75
MDL编号	MFCD17215962
PubChem化学物质编号	329819977

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
储存条件	protect from light
颜色	white to off-white
溶解性	DMSO: >20 mg/mL
储存温度	2-8℃
SMILES string	OC(=O)\C=C(\CCc1ccc(Cl)cc1)c2ccccc2
InChI	1S/C17H15ClO2/c18-16-10-7-13(8-11-16)6-9-15(12-17(19)20)14-4-2-1-3-5-14/h1-5,7-8,10-12H,6,9H2,(H,19,20)/b15-12-
InChI key	LLJYFDRQFPQGNY-QINSGFPZSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable