产品说明
应用
Rc-Ome may be used in GABAA-mediated cell signaling studies.
包装
5, 25 mg in glass bottle
生化/生理作用
Rc-OMe is a GABAA PAM that distinguishes α1β2γ2s from α1β2 receptors. The compound has very weak potentiating effects on α1β2, but potentiates GABA-elicited currents of α(123)β2γ2s receptors, all with low μM EC50s. Rc-OMe acts at a binding site that is distinct from BDZ, pentobarbital and loreclezole modulatory sites.
特点和优势
This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
基本信息
经验(实验)分子式 | C17H16O4 |
分子量 | 284.31 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | , light to dark yellow |
溶解性 | DMSO: ≥10 mg/mL |
储存温度 | 2-8℃ |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H400 |
预防措施声明 | P273 |
危险分类 | Aquatic Acute 1 |
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |