产品说明
应用
Reversan may be used in cell signaling studies.
包装
5, 25 mg in glass bottle
生化/生理作用
Reversan increases the efficacy of vincristine and etoposide and increases the sensitivity of murine models of neuroblastoma to conventional chemotherapy.
Reversan is a selective and nontoxic multidrug resistance-associated protein 1 (MRP1) and P-glycoprotein (P-gp) inhibitor.
基本信息
经验(实验)分子式 | C26H27N5O2 |
分子量 | 441.52 |
MDL编号 | MFCD01528184 |
PubChem化学物质编号 | 329825203 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | faintly yellow to yellow |
溶解性 | DMSO: ≥8 mg/mL at ~60 ℃ |
储存温度 | 2-8℃ |
SMILES string | O=C(NCCCN1CCOCC1)c2cnn3c(cc(nc23)-c4ccccc4)-c5ccccc5 |
InChI | 1S/C26H27N5O2/c32-26(27-12-7-13-30-14-16-33-17-15-30)22-19-28-31-24(21-10-5-2-6-11-21)18-23(29-25(22)31)20-8-3-1-4-9-20/h1-6,8-11,18-19H,7,12-17H2,(H,27,32) |
InChI key | JTRXWCLQFAZHGP-UHFFFAOYSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |