产品说明
生化/生理作用
NR2B-selective, noncompetitive NMDA glutamate receptor antagonist
特点和优势
This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
基本信息
| 经验(实验)分子式 | C21H23FN2O3 · HCl |
| 分子量 | 406.88 |
| MDL编号 | MFCD03101333 |
| PubChem化学物质编号 | 24277971 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 形式 | solid |
| 溶解性 | H2O: ≤0.5 mg/mL |
| 创始人 | Roche |
| 储存温度 | 2-8℃ |
| SMILES string | Cl.NC(=O)c1ccc(OCCC(O)N2CCC(=CC2)c3ccc(F)cc3)cc1 |
| InChI | 1S/C21H23FN2O3.ClH/c22-18-5-1-15(2-6-18)16-9-12-24(13-10-16)20(25)11-14-27-19-7-3-17(4-8-19)21(23)26;/h1-9,20,25H,10-14H2,(H2,23,26);1H |
| InChI key | NYFXHCMXYODFLP-UHFFFAOYSA-N |
| Gene Information | human ... GRIN2B(2904) |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H315 - H319 - H335 |
| 预防措施声明 | P302 + P352 - P305 + P351 + P338 |
| 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
Sigma-Aldrich
m.cnreagent.com
