T2AA hydrochloride

产品名称：

1380782-27-3
T2AA hydrochloride
(S)-4-(4-(2-amino-3-hydroxypropyl)-2,6-diiodophenoxy)phenol hydrochloride
T2-aminoalcohol hydrochloride

产品介绍：

产品说明

应用

T2AA hydrochloride has been used as a chemical inhibitor of proliferating cell nuclear antigen (PCNA) in vaccinia virus.

包装

5, 25 mg in glass bottle

生化/生理作用

T2AA is an inhibitor of PCNA/ PIP-Box interactions that binds to the PCNA cavity that interacts with PIP-Box sequences. Also T2AA inhibits PCNA Polδ3 interaction. T2AA inhibits de novo DNA synthesis, and in combination of cisplatin significantly increases growth inhibition in cancer cells. T2AA is a T3 analog that exhibits almost no thyroid hormone activity.

基本信息

经验(实验)分子式	C₁₅H₁₅I₂NO₃ · HCl
分子量	547.55
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 10 mg/mL, clear
储存温度	2-8℃

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable