U-104

产品名称：

178606-66-1
U-104
NSC 213841
4-[[[(4-Fluorophenyl)amino]carbonyl]amino]-benzenesulfonamide

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

U-104 is an inhibitor of CA IX that binds only to CA IX under hypoxic conditions in vivo. The binding results in significant inhibition of tumor growth and metastasis formation in both spontaneous and experimental models of metastasis. U-104 reduces the medium acidity by inhibiting the catalytic activity of the CA IX. It binds specifically only to hypoxic cells expressing CA IX.

基本信息

经验(实验)分子式	C₁₃H₁₂FN₃O₃S
分子量	309.32
MDL编号	MFCD00159265
PubChem化学物质编号	329825375
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: >15 mg/mL
储存温度	2-8℃
SMILES string	O=C(NC1=CC=C(S(N)(=O)=O)C=C1)NC2=CC=C(F)C=C2
InChI	1S/C13H12FN3O3S/c14-9-1-3-10(4-2-9)16-13(18)17-11-5-7-12(8-6-11)21(15,19)20/h1-8H,(H2,15,19,20)(H2,16,17,18)
InChI key	YJQZNWPYLCNRLP-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable