产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
Taurolidine is an antibacterial agent that can be used for the treatment of peritonis. It has also been used as an antiendoxic substance for systematic inflammatory response syndrome and as an anti-angiogenic agent for tumors. Furthermore, studies have reported that taurolidine can be used for the prevention of multiple catheter-related bloodstream infections.
滔罗林是一种具有抗肿瘤活性的广谱抗生素，可以引起细胞凋亡并减少肿瘤细胞增殖。滔罗林已与肿瘤坏死因子相关凋亡诱导配体 (TRAIL) 搭配使用以描述许多细胞凋亡相关信号蛋白的协同反应。由于无毒的滔罗林可以降低重组人肿瘤坏死因子相关凋亡诱导配体 (rhTRAIL) 的毒性和剂量，因此滔罗林与 rhTRAIL 联用的治疗方式可以为癌症治疗提供新的选择。滔罗林也被用作研究细胞凋亡和坏死的多种机理的工具。
制备说明
Taurolidine is soluble in DMSO at a concentration that is greater than 20 mg/ml.
基本信息
| 经验(实验)分子式 | C7H16N4O4S2 |
| 分子量 | 284.36 |
| EC 号 | 243-016-5 |
| MDL编号 | MFCD00865076 |
| PubChem化学物质编号 | 329826864 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | >97% (NMR) |
| 形式 | powder |
| 储存条件 | protect from light |
| 颜色 | white to off-white |
| 溶解性 | DMSO: >20 mg/mL |
| 储存温度 | room temp |
| SMILES string | O=S1(=O)CCN(CN1)CN2CCS(=O)(=O)NC2 |
| InChI | 1S/C7H16N4O4S2/c12-16(13)3-1-10(5-8-16)7-11-2-4-17(14,15)9-6-11/h8-9H,1-7H2 |
| InChI key | AJKIRUJIDFJUKJ-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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