产品说明
一般描述
THPN or 1-(3,4,5-Trihydroxyphenyl)nonan-1-one, is a derivative of cytosporone B.
包装
5, 25 mg in glass bottle
生化/生理作用
THPN is potent nuclear receptor TR3 (Nur77) antagonist that induces autophagic cell death in melanoma. Co-application of THPN with Akt2 inhibitors significantly represses tumor growth in xenograft mouse model.
其他说明
air sensitive
基本信息
经验(实验)分子式 | C15H22O4 |
分子量 | 266.33 |
PubChem化学物质编号 | 329825957 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | white to beige |
溶解性 | DMSO: 25 mg/mL, clear |
储存温度 | 2-8℃ |
SMILES string | OC1=C(O)C(O)=CC(C(CCCCCCCC)=O)=C1 |
InChI | 1S/C15H22O4/c1-2-3-4-5-6-7-8-12(16)11-9-13(17)15(19)14(18)10-11/h9-10,17-19H,2-8H2,1H3 |
InChI key | NVFRHTFJDGAFQS-UHFFFAOYSA-N |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 |
预防措施声明 | P301 + P312 + P330 |
危险分类 | Acute Tox. 4 Oral |
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich