产品说明
应用
UCL 2077 has been used for slow afterhyperpolarization (sAHP) studies in thalamic paraventricular nucleus (PVT) neurons. UCL 2077 has also been used for studying its effects on the increase in excitability of hippocampal pyramidal cells.
包装
5, 25 mg in glass bottle
生化/生理作用
UCL 2077 is a slow afterhyperpolarization (sAHP) channel blocker.
制备说明
UCL 2077 is soluble in DMSO at a concentration >20 mg/ml and is insoluble in water.
基本信息
经验(实验)分子式 | C25H22N2 |
分子量 | 350.46 |
MDL编号 | MFCD00585879 |
PubChem化学物质编号 | 329827644 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | solid |
颜色 | white |
溶解性 | DMSO: soluble >20 mg/mL H2O: insoluble |
SMILES string | C(NC(c1ccccc1)(c2ccccc2)c3ccccc3)c4cccnc4 |
InChI | 1S/C25H22N2/c1-4-12-22(13-5-1)25(23-14-6-2-7-15-23,24-16-8-3-9-17-24)27-20-21-11-10-18-26-19-21/h1-19,27H,20H2 |
InChI key | PQFNWDHABGBCHB-UHFFFAOYSA-N |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 - H315 - H319 - H335 |
预防措施声明 | P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 |
危险分类 | Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
靶器官 | Respiratory system |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
Sigma-Aldrich