VU0409551

产品名称：

1363281-27-9
VU0409551
JNJ 46778212
JNJ-46778212
VU 0409551
[6,7-Dihydro-2-(phenoxymethyl)oxazolo[5,4-c]pyridin-5(4H)-yl](4-fluorophenyl)methanone

产品介绍：

产品说明

生化/生理作用

VU0409551 (JNJ-46778212) is an orally available, potent and selective biased metabotropic glutamate receptor subtype 5 positive allosteric modulator (mGlu5 PAM). VU0409551 (JNJ-46778212) selectively potentiates mGlu5 coupling to Gaq-mediated signaling without modulation of NMDAR currents in hippocampal neurons. VU0409551 exhibits potent antipsychotic-like and cognition enhancing activity in animal models.

基本信息

经验(实验)分子式	C₂₀H₁₇FN₂O₃
分子量	352.36
MDL编号	MFCD29047143

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
储存温度	2-8℃
SMILES string	O=C(N1CCC2=C(C1)OC(COC3=CC=CC=C3)=N2)C4=CC=C(C=C4)F

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable