Y-39983 dihydrochloride

产品名称：

173897-44-4
Y-39983 dihydrochloride
4-[(1R)-1-Aminoethyl]-N-1H-pyrrolo[2,3-b]pyridin-4-yl-benzamide dihydrochloride
Y39983
Y 39983

产品介绍：

产品说明

生化/生理作用

Y-39983 is a potent and selective Rho-kinase (ROCK) inhibitor (IC₅₀s = 3.6 nM). Y-39983 is 10 fold more potent in promoting the outgrowth of neurites in cultured retinal slices and axonal regeneration in crushed optic nerve models than Y-27632. Y-39983 act also as an activator of the neuroprotective Parkin-mediated mitophagy pathway.

基本信息

经验(实验)分子式	C₁₆H₁₆N₄O · 2HCl
分子量	353.25
MDL编号	MFCD00945328

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
旋光性	[α]/D +5 to +9°, c = 1 in methanol
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
储存温度	−20℃
SMILES string	N[C@@H](C1=CC=C(C(NC2=CC=NC3=C2C=CN3)=O)C=C1)C.Cl.Cl

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable