产品说明
一般描述
Melatonin and its metabolites are being studied for their antioxidant properties and their protective effects against oxidative stress in both mammals and in plants. N1-Acetyl-5-methoxykynuramine (AMK) and its direct precursor N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) are two metabolites that contribute to the antioxidant properties of melatonin.
应用
Metabolomics research
生化/生理作用
AFMK is a melatonin metabolite first detected in rat brain; demonstrates antioxidant and free radical scavenging activities in several experimental models; inhibits LPS-mediated production of TNFα and IL-8 in neutrophils; useful tool in the study of melatonin metabolism.
基本信息
经验(实验)分子式 | C13H16N2O4 |
分子量 | 264.28 |
MDL编号 | MFCD02683241 |
产品性质
质量水平 | 200 |
测定 | ≥95% (HPLC) |
形式 | solid |
储存温度 | 2-8℃ |
SMILES string | COc1ccc(NC=O)c(c1)C(=O)CCNC(C)=O |
安全信息
象形图 | |
警示用语: | Danger |
危险声明 | H301 |
预防措施声明 | P264 - P270 - P301 + P310 - P405 - P501 |
危险分类 | Acute Tox. 3 Oral |
储存分类代码 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich