(2′Z,3′E)-6-Bromoindirubin-3′-acetoxime

产品名称：

667463-85-6
BIO-Acetoxime
BIA
6-Bromoindirubin acetoxime
(3Z)-3-[(3E)-3-[(Acetyloxy)imino]-1,3-dihydro-2H-indol-2-ylidene]-6-bromo-1,3-dihydro-2H-Indol-2-one
6-Bromoindirubin-3′-acetoxime
(2′Z,3′E)-6-Bromoindirubin-3′-acetoxime

产品介绍：

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

BIO-Acetoxime is a potent and selective GSK-3a/b inhibitor that reduces invasiveness of gliomas and extends animal survival in intracranial glioma models. Also, BIO-Acetoxime induces Wnt signaling and inhibits CD8+ T cell effector differentiation.

特点和优势

This compound is featured on the GSK-3 page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式	C₁₈H₁₂BrN₃O₃
分子量	398.21
MDL编号	MFCD09037533
PubChem化学物质编号	329825535
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	, dark red to purple
溶解性	H₂O: 2 mg/mL (clear solution, warmed)
储存温度	2-8℃
SMILES string	CC(=O)O\N=C1\C(Nc2ccccc12)=C3\C(=O)Nc4cc(Br)ccc34
InChI	1S/C18H12BrN3O3/c1-9(23)25-22-16-12-4-2-3-5-13(12)20-17(16)15-11-7-6-10(19)8-14(11)21-18(15)24/h2-8,20H,1H3,(H,21,24)/b17-15-,22-16+
InChI key	MENDIXKFTXYTHJ-HPBPSMLHSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302 - H410
预防措施声明	P273 - P301 + P312 + P330
危险分类	Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable