产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
CGP36742 was the first orally active GABAB-selective antagonist. The IC50 for blocking GABAergic transmission is 36 μM. Oral administration of CGP36742 in rats blocks baclofen-induced neuronal depression, and reduces learning deficit and passive avoidance in an olfactory bulbectomy depression model.
特点和优势
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基本信息
经验(实验)分子式 | C7H18NO2P |
分子量 | 179.20 |
MDL编号 | MFCD00882735 |
PubChem化学物质编号 | 329825430 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥97% (NMR) |
形式 | powder |
储存条件 | desiccated |
颜色 | white to beige |
溶解性 | H2O: 10 mg/mL (clear solution, warmed) |
储存温度 | room temp |
SMILES string | CCCCP(O)(=O)CCCN |
InChI | 1S/C7H18NO2P/c1-2-3-6-11(9,10)7-4-5-8/h2-8H2,1H3,(H,9,10) |
InChI key | ONNMDRQRSGKZCN-UHFFFAOYSA-N |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 - H319 |
预防措施声明 | P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313 |
危险分类 | Acute Tox. 4 Oral - Eye Irrit. 2 |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich