产品说明
一般描述
N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone is a tetrapeptide, cell-permeable and non-cytotoxic inhibitor.
应用
N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone has been used as an elastase specific inhibitor.
生化/生理作用
N-(Methoxysuccinyl)-Ala-Ala-Pro-Val-chloromethyl ketone acts as a competitive inhibitor of human leukocyte elastase (HLE).
Irreversible inhibitor of human leukocyte and neutrophil elastase.
基本信息
| 经验(实验)分子式 | C22H35ClN4O7 |
| 分子量 | 502.99 |
| Beilstein | 6167019 |
| MDL编号 | MFCD00077136 |
| PubChem化学物质编号 | 24896552 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 200 |
| 测定 | ≥98% (TLC) |
| 形式 | powder |
| mp | 159 ℃ |
| 溶解性 | methanol: 50 mg/mL, clear, colorless |
| 储存温度 | −20℃ |
| SMILES string | COC(=O)CCC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)CCl |
| InChI | 1S/C22H35ClN4O7/c1-12(2)19(16(28)11-23)26-21(32)15-7-6-10-27(15)22(33)14(4)25-20(31)13(3)24-17(29)8-9-18(30)34-5/h12-15,19H,6-11H2,1-5H3,(H,24,29)(H,25,31)(H,26,32)/t13-,14-,15-,19-/m0/s1 |
| InChI key | PJGDFLJMBAYGGC-XLPNERPQSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich
m.cnreagent.com
