5-Bromo-2′-deoxyuridine 5′-triphosphate sodium salt

产品名称：

102212-99-7
5-Bromo-2′-deoxyuridine 5′-triphosphate sodium salt
5-BrdUTP

产品介绍：

产品说明

一般描述

5-Bromo-2′-deoxyuridine 5′-triphosphate is used for incorporation into DNA for studying normal and tumor cell proliferation profiles.

应用

5-Bromo-2′-deoxyuridine 5′-triphosphate (5-BrdUTP) may be used as a labeling TdT substrate for terminal deoxynucleotidyl transferase (TdT) reactions or for DNA synthesis. BrdUTP is also used as an effective mutagenic agent. 5-BrdUTP labeling may be detected by immunological techniques or 5-BrdUTP may be derivitized by biotinylation or other methods for detection by fluorogenic or chromogenic methods.
5-Bromo-2′-deoxyuridine 5′-triphosphate sodium salt has been used:

in the labelling of 3′-OH termini of fragmented DNA with double stranded breaks in african green monkey kidney cells
to label cleaved DNA ends in apoptosis assay in avian tissue sections
for incorporation into mice prostates for immunohistochemistry studies

包装

25 mg in poly bottle
1, 5 mg in glass bottle

基本信息

经验(实验)分子式	C₉H₁₄BrN₂O₁₄P₃
分子量	547.04
MDL编号	MFCD00057405
PubChem化学物质编号	24891527
NACRES	NA.51

产品性质

质量水平	200
生物来源	synthetic (organic)
测定	≥90%
形式	powder
溶解性	water: 50 mg/mL, clear, colorless to faintly yellow
储存温度	−20℃
SMILES string	[Na].OC1CC(OC1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)N2C=C(Br)C(=O)NC2=O
InChI	1S/C9H14BrN2O14P3.Na.H/c10-4-2-12(9(15)11-8(4)14)7-1-5(13)6(24-7)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;/h2,5-7,13H,1,3H2,(H,19,20)(H,21,22)(H,11,14,15)(H2,16,17,18);;
InChI key	UWZGQOWZUSBZMC-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
个人防护装备	Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges