产品说明
应用
Nα-Benzoyl-DL-arginine β-naphthylamide hydrochloride has been used as a substrate in the BANA test to evaluate the inhibitory activity of stefin. It has also been used as a substrate for the determination of Ki values of inhibitors toward trypsin.
生化/生理作用
Nα-Benzoyl-DL-arginine β-naphthylamide hydrochloride (BANA) helps to determine the activities of cathepsin B and papain. BANA test is also useful in identifying the number of periodontal sites with periodontal pathogens. Presence of volatile sulfur compounds (VSCs), synthesized by oral bacteria in dental plaque or tongue coating can be colorimetrically confirmed by their ability to hydrolyze N-benzoyl-DL-arginine-2-naphthylamide.
底物
A chromogenic substrate for trypsin.
基本信息
| 经验(实验)分子式 | C23H25N5O2 · HCl |
| 分子量 | 439.94 |
| Beilstein | 3823291 |
| EC 号 | 213-015-4 |
| MDL编号 | MFCD00038940 |
| PubChem化学物质编号 | 24891699 |
| NACRES | NA.32 |
产品性质
| 质量水平 | 200 |
| 测定 | ≥98% (TLC) |
| 形式 | powder |
| 溶解性 | DMF: 50 mg/mL, clear, colorless to faintly yellow |
| 储存温度 | 2-8℃ |
| SMILES string | Cl[H].NC(=N)NCCCC(NC(=O)c1ccccc1)C(=O)Nc2ccc3ccccc3c2 |
| InChI | 1S/C23H25N5O2.ClH/c24-23(25)26-14-6-11-20(28-21(29)17-8-2-1-3-9-17)22(30)27-19-13-12-16-7-4-5-10-18(16)15-19;/h1-5,7-10,12-13,15,20H,6,11,14H2,(H,27,30)(H,28,29)(H4,24,25,26);1H |
| InChI key | BNGRKDJZQIGWQF-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich
m.cnreagent.com
