产品说明
一般描述
Fibrinogen-like protein 2 (FGL2) is a transmembrane prothrombinase, that belongs to the fibrinogen-like protein family. It is located on human chromosome 7q11.23.
免疫原
FGL2 (NP_006673.1, 1 a.a. ~ 439 a.a) full-length human protein.
Sequence
MKLANWYWLSSAVLATYGFLVVANNETEEIKDERAKDVCPVRLESRGKCEEAGECPYQVSLPPLTIQLPKQFSRIEEVFKEVQNLKEIVNSLKKSCQDCKLQADDNGDPGRNGLLLPSTGAPGEVGDNRVRELESEVNKLSSELKNAKEEINVLHGRLEKLNLVNMNNIENYVDSKVANLTFVVNSLDGKCSKCPSQEQIQSRPVQHLIYKDCSDYYAIGKRSSETYRVTPDPKNSSFEVYCDMETMGGGWTVLQARLDGSTNFTRTWQDYKAGFGNLRREFWLGNDKIHLLTKSKEMILRIDLEDFNGVELYALYDQFYVANEFLKYRLHVGNYNGTAGDALRFNKHYNHDLKFFTTPDKDNDRYPSGNCGLYYSSGWWFDACLSANLNGKYYHQKYRGVRNGIFWGTWPGVSEAHPGGYKSSFKEAKMMIRPKHFKP
生化/生理作用
Fibrinogen-like protein 2 (FGL2) may induce the progression of glioblastoma multiforme (GBM) cancer by stimulating multiple immune-suppression mechanisms. It performs several functions like prothrombinase activity and immune regulatory roles in viral infection, allograft rejection and abortion. FGL2 has the ability to directly cleave prothrombin to thrombin.
外形
Solution in phosphate buffered saline, pH 7.4
基本信息
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 50.2 kDa |
| species reactivity | human |
| technique(s) | western blot: 1 μg/mL |
| NCBI登记号 | NM_006682.2 |
| UniProt登记号 | Q14314 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... FGL2(10875) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
