产品说明
一般描述
The kirsten rat sarcoma-2 virus oncogene (KRAS) gene is mapped to human chromosome 12p12.1 and belongs to the family of Ras genes. The protein encoded is a small guanosine nucleotide-bound GTPases belonging.
免疫原
KRAS purified recombinant protein
生化/生理作用
Mutation in the KRAS gene causes non small-cell lung cancer and promotes tumor initiation, progression and metastasis. Altered KRAS gene also offers resistance to chemotherapy. It is involved in the signal transduction between epidermal growth factor receptor (EGFR) to the nucleus.
外形
Solution in Dulbecco′s Modified Eagle′s Medium with 10% fetal calf serum and 15 mM sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
产品性质
| 质量水平 | 200 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified from hybridoma cell culture |
| antibody product type | primary antibodies |
| 克隆 | KRAS-A582, monoclonal |
| 形式 | aqueous solution |
| 分子量 | antigen predicted mol wt 27.9 kDa |
| species reactivity | human |
| technique(s) | western blot: suitable using 1:250-1:500 using HEK-293 cells expressing KRAS |
| 同位素/亚型 | IgG1 |
| UniProt登记号 | P01116 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... KRAS(3845) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
