产品说明
一般描述
Protein arginine methyltransferase 1 (PRMT1) gene is localized on human chromosome 19q13.33. It is part of the type I PRMT family.
特异性
Does not cross-react with PRMT2, 3, 4, and 5.
免疫原
full length PRMT1. Does not cross-react with PRMT2, 3, 4, and 5.
应用
Anti-PRMT1 antibody, Mouse monoclonal has been used for Immunofluorescence and Western Blotting.
包装
200 μL in glass insert
生化/生理作用
Protein arginine methyltransferase 1 (PRMT1) is crucial for the formation of asymmetric dimethylarginine. It can methylate Twist-1, a transcription factor. The protein also methylates histones and thus modulates transcription and protein activity. PRMT1 is involved in epithelial-mesenchymal transition and may have a role in cancer.
外形
0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。
储存及稳定性
For continuous use, store at 2-8 C for up to one month. For prolonged storage, freeze in working aliquots at 20 C. Repeated freezing and thawing, or storage in frost-free freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
MDL编号 | MFCD04975120 |
产品性质
质量水平 | 200 |
生物来源 | mouse |
偶联物 | unconjugated |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | PRMT1-171, monoclonal |
形式 | buffered aqueous solution |
分子量 | antigen ~42 kDa |
species reactivity | canine, monkey, hamster, bovine, human, mouse, rat, chicken |
浓度 | ~2 mg/mL |
technique(s) | immunoprecipitation (IP): suitable indirect ELISA: suitable western blot: 2 μg/mL using whole cell extract of 293T cells |
同位素/亚型 | IgG1 |
UniProt登记号 | Q99873 |
运输 | dry ice |
储存温度 | −20℃ |
Gene Information | human ... PRMT1(3276) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich