产品说明
一般描述
Stromal interaction molecule 2 (STIM2) plays an important role in mediating store-operated Ca2+ entry (SOCE), a Ca2+ influx following depletion of intracellular Ca2+ stores. It inhibits STIM1-mediated store-operated Ca++ entry; however, STIM2 can form complexes with STIM1. This suggests that STIM1 and STIM2 may play a coordinated role in controlling Ca++ entry. STIM2 is expressed in all tissues and tumor cell lines examined.
特异性
This antibody recognizes the intermediate domain of STIM2.
免疫原
Epitope: Intermediate domain
KLH-conjugated linear peptide corresponding to the intermediate domain of human STIM2.
应用
Detect Stromal interaction molecule 2 using this rabbit polyclonal antibody, Anti-STIM2 Antibody validated for use in western blotting, IHC (Paraffin) & Immunofluorescence.
Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected STIM2 in human spleen tissue.
Immunofluorescence Analysis: 20 μg/mL from a representative lot detected STIM2 in human spleen cells.
Research Sub Category
Immunoglobulins & Immunology
Research Category
Inflammation & Immunology
质量
Evaluated by Western Blotting in A-20 cell lysate.
Western Blotting Analysis: 2 µg/mL of this antibody detected STIM2 in 15 µg of A-20 cell lysate.
目标描述
~98 kDa observed
外形
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Antigen Affinity Purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
A-20 cell lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | mouse, human |
technique(s) | immunofluorescence: suitable immunohistochemistry: suitable (paraffin) western blot: suitable |
UniProt登记号 | Q9P246 |
运输 | wet ice |
Gene Information | human ... STIM2(57620) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich