Anti-Puma BH3 domain Antibody

产品说明

一般描述

PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis

特异性

Other species have not been tested.
The antibody reacts with the 21 kDa Puma BH3 domain protein.

免疫原

This antibody was developed against a synthetic peptide selected from the C-terminal region of human Puma.

应用

Anti-Puma BH3 domain Antibody is an antibody against Puma BH3 domain for use in WB.

质量

Western Blot Analysis: 1:250 dilution of this antibody detected Puma BH3 domain on mouse brain lysate.

目标描述

21 kDa

外形

Protein G Purified
Format: Purified

分析说明

Control
Western Blot : Mouse brain lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

产品性质

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