产品说明
一般描述
NOTCH homolog-4 (NOTCH4) is expressed in breast cancer.
免疫原
synthetic peptide corresponding to residues 1506-1524 of human NOTCH4. This sequence is 89% identical in mouse and rat.
生化/生理作用
NOTCH homolog-4 (NOTCH4) has an intracellular domain which detaches from the protein on activation. This domain then translocates to the nucleus and modulates transcription of genes. NOTCH4 also activates various pathways and contributes to carcinogenesis. Mutations in the gene encoding the protein may be linked to schizophrenia.
外形
solution in phosphate buffered saline, containing 0.02% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 200 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen ~230 kDa antigen ~80 kDa |
| species reactivity | human, mouse, rat |
| 浓度 | ~1 mg/mL |
| technique(s) | immunohistochemistry: 1:100-1:200 western blot: 1:500-1:1,000 |
| UniProt登记号 | Q99466 |
| application(s) | research pathology |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... NOTCH4(4855) mouse ... Notch4(18132) rat ... Notch4(406162) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
Sigma-Aldrich
m.cnreagent.com
