Anti-GLUT1 antibody produced in rabbit

产品名称：

Anti-GLUT1 antibody produced in rabbit
HepG2 glucose transporter
SLC2A1
Glucose transporter type 1 erythrocyte/brain
Solute carrier family 2 facilitated glucose transporter member 1
GLUT-1

产品介绍：

产品说明

一般描述

Anti-GLUT1 Antibody detects endogenous levels of total GLUT1 protein.
GLUT1 (Glucose transporter type 1) gene is located on human chromosome 1p34.2. It is expressed in cerebral endothelial cells.

免疫原

The antiserum was produced against synthesized peptide derived from human GLUT1.

Immunogen Range: 441-490

应用

Anti-GLUT1, C-Terminal antibody is suitable for use in western blot and immunohistochemistry.
Anti-GLUT1 antibody produced in rabbit has been used

for protein extraction
in western blotting
for immunohistochemistry

生化/生理作用

GLUT1 is a membrane protein that regulates the facilitative transport of glucose across the cells. Mutations in the gene encoding GLUT1 have been linked to epilepsy and diabetic nephropathy . Increased expression of GLUT1 has been associated with tumor differentiation in breast and endometrial cancers, whereas decreased GLUT1 function causes GLUT1 deficiency syndrome . Anti-GLUT1, C-Terminal antibody can be used to detect endogenous levels of total GLUT1 protein. The antibody specifically reacts with GLUT1 in mice, rats and humans.
GLUT1 (Glucose transporter type 1) functions as a receptor for human T-cell leukemia virus (HTLV) I and II. It plays a key role in HTLV-envelope mediated infection. GLUT1 is associated with paroxysmal exertion-induced dyskinesia. Glut1 may regulate cerebral microvasculature, proliferation of endothelial cells and the development of junctional complexes of the BBB (blood-brain barrier). It transports glucose across the BBB.

特点和优势

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外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES

NA.41

产品性质

生物来源	rabbit
质量水平	100
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
分子量	antigen 54 kDa
species reactivity	mouse, rat, human
浓度	~1 mg/mL
technique(s)	ELISA: 1:40000 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000
NCBI登记号	P11166
UniProt登记号	P11166
运输	wet ice
储存温度	−20℃
Gene Information	human ... SLC2A1(6513)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	nwg
闪点(F)	Not applicable
闪点(C)	Not applicable