产品说明
一般描述
Periostin (POSTN) is also known as osteoblast-specific factor-2. It is a 90 kDa protein expressed in the extracellular matrix and bones. POSTN is an adhesive glycoprotein. The gene encoding this protein is localized on human chromosome 13q13.3.
免疫原
human Periostin recombinant protein. The human protein shares 87% homology with the mouse protein.
应用
Monoclonal Anti-Periostin antibody produced in mouse has been used to develop a periostin imaging PET probe.
生化/生理作用
Periostin (POSTN) has a role in the differentiation and cell adhesion of osteogenic cells. It functions as a biomarker of T-helper cells type 2-mediated inflammatory diseases. The protein has been associated with various cancers. POSTN is involved in epithelial-mesenchymal transition and extracellular matrix degradation.
外形
0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified from hybridoma cell culture |
| antibody product type | primary antibodies |
| 克隆 | 47, monoclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen ~88 kDa |
| species reactivity | human |
| 浓度 | ~1.0 mg/mL |
| technique(s) | western blot: 2-4 μg/mL using whole extracts of HEK-293T cells over expressing human Periostin |
| 同位素/亚型 | IgG1 |
| UniProt登记号 | Q15063 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... POSTN(10631) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
