Anti-Nicotinic Acetylcholine Receptor β2 Antibody

产品说明

一般描述

Nicotinic acetylcholine receptors, also known as nAChRs, belong to a family of proteins called ligand gated ion channels and are widely expressed throughout the nervous system. nAChRs are made up of 5 subunits (two α and three β). Subunits α4 and β2 (α4β2) is the main receptor in the mammalian brain and has been associated with the positive reinforcing effects of nicotine. The relative contribution of nAChRs β2 and β4 are not well understood because the subunit structure that mediates synaptic transmission in the peripheral nervous system is unknown.

特异性

This antibody recognizes Nicotinic Acetylcholine Receptor β2.

免疫原

This antibody is generated from rabbits immunized with a KLH-conjugated linear peptide selected from residues of Nicotinic Acetylcholine Receptor β2.

应用

Detect Nicotinic Acetylcholine Receptor β2 using this Anti-Nicotinic Acetylcholine Receptor β2 Antibody validated for use in WB.

质量

Routinely evaluated by Western Blot in rat e16 brain lysate.
Western Blot Analysis: : 1:20,000 dilution of this lot detected Nicotinic Acetylcholine Receptor β2 on 10 µg of rat e16 brain lysate.

目标描述

Approx. 55 kDa

外形

Affinity purified

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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