Anti-Caspase-14 Antibody

产品说明

一般描述

Caspases are a family of cysteine proteases that can be divided into apoptotic and inflammatory caspase subfamilies. Caspase-14 exists as 2 subunits (p19 and p10) and is highly expressed in embryonic but not adult tissues. It is processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in the keratinocyte terminal differentiation, which is important for the formation of the skin barrier.

特异性

This antibody detects the pro-form of Caspase-14 as well as the large subunit cleaved form.

免疫原

KLH-conjugated linear peptide corresponding to 16 amino acids near the C-terminus of human Caspase-14.

应用

Anti-Caspase-14 Antibody is a highly specific rabbit polyclonal antibody, that targets Caspase 14 & has been tested in western blotting & IHC.
Immunohistochemistry Analysis: 2.5 μg/mL from a representative lot detected Caspase-14 in human liver tissue.

质量

Evaluated by Western Blotting in Jurkat cell lysate with and without blocking peptide.

Western Blotting Analysis: 1 μg/mL of this antibody detected Caspase-14 in Jurkat cell lysate with and without blocking peptide.

目标描述

~28 kDa observed. Uncharacterized bands may be observed in some lysate(s).

外形

Antigen Affinity Purified

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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