Anti-phospho-STAT2 (pTyr<sup>690</sup>) antibody produced in rabbit

产品名称：

Anti-phospho-STAT2 (pTyr⁶⁹⁰) antibody produced in rabbit

产品介绍：

产品说明

一般描述

STAT2 (signal transducer and activator of transcription 2) is mapped to human chromosome 12.
Signal transducer and activator of transcription 2 (STAT2) belongs to the STAT family. The gene is located on human chromosome 12q13.3. STAT2 consists of 24 exons and has a molecular weight of 113 kDa. It consists of N-terminal domain (N), coiled-coil domain (CC), DNA-binding domain (DBD), linker domain (L), Src homology 2 domain (SH2), tyrosine phosphorylation site (Y) and transcriptional activation domain (TAD).

免疫原

The antiserum was produced against synthesized peptide derived from human STAT2 around the phosphorylation site of Tyr690.

Immunogen Range: 656-705

应用

Anti-phospho-STAT2 (pTyr690) antibody produced in rabbit has been used in western blotting, immunofluorescence staining and flow cytometric staining.
Anti-phospho-STAT2 (pTyr⁶⁹⁰) antibody produced in rabbit has been used:

for western blotting
for immunofluorescence staining
for flow cytometric staining

生化/生理作用

STAT2 (signal transducer and activator of transcription 2) participates in immunity. It plays a major role in interferon signaling pathways.
Signal transducer and activator of transcription 2 (STAT2) is activated by interferon-1 (IFN-I) and IFN-III. It aids protein-protein interactions and is essential for binding IRF9. STAT2 is required for the nuclear export of STAT2-IFN regulatory factor 9 (IRF9) and IFN-stimulated gene factor 3 (ISGF3). It plays a vital role in interactions with STAT1.

特点和优势

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外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES

NA.41

产品性质

生物来源	rabbit
质量水平	100
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
分子量	antigen 97 kDa
species reactivity	mouse, human, rat
浓度	~1 mg/mL
technique(s)	ELISA: 1:20000 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000
NCBI登记号	P52630
UniProt登记号	P52630
运输	wet ice
储存温度	−20℃
Gene Information	human ... STAT2(6773)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable