产品说明
一般描述
Dimethyl chloromalonate (dimethyl 2-chloromalonate) is a dialkyl 2-substituted malonate. Carbanions of dimethyl chloromalonate are reported to react with naphthoquinone derivatives, via vicarious nucleophilic substitution or oxidative nucleophilic substitution of hydrogen processes. Dimethyl chloromalonate is reported to react with hydroquinone and monosubstituted hydroquinones to afford 2-oxido-benzo[b]furan derivatives. Synthesis of dimethyl 2-chloromalonate, via chlorination of dimethyl malonate has been reported.
应用
Dimethyl chloromalonate is suitable for use in the synthesis of 4,5,6-trichloropyrimidine. It may be used in the stereoselective synthesis of highly functionalized nitrocyclopropanes. It may be used in one-pot synthesis of tetra-alkoxycarbonylallylidenetriphenylphosphoranes.
包装
25, 100 g in glass bottle
基本信息
| 线性分子式 | ClCH(COOCH3)2 |
| 分子量 | 166.56 |
| Beilstein | 1768415 |
| EC 号 | 249-275-0 |
| MDL编号 | MFCD00042837 |
| PubChem化学物质编号 | 24863315 |
| NACRES | NA.22 |
产品性质
| 质量水平 | 200 |
| 测定 | 94% |
| 杂质 | 4-5% dimethyl dichloromalonate |
| 折射率 | n |
| bp | 105-106 ℃/19 mmHg (lit.) |
| 密度 | 1.305 g/mL at 25 ℃ (lit.) |
| SMILES string | COC(=O)C(Cl)C(=O)OC |
| InChI | 1S/C5H7ClO4/c1-9-4(7)3(6)5(8)10-2/h3H,1-2H3 |
| InChI key | LNBQBURECUEBKZ-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Danger |
| 危险声明 | H314 |
| 预防措施声明 | P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405 |
| 危险分类 | Skin Corr. 1B |
| 储存分类代码 | 8A - Combustible, corrosive hazardous materials |
| WGK | WGK 3 |
| 闪点(F) | 224.6 °F - closed cup |
| 闪点(C) | 107 ℃ - closed cup |
| 个人防护装备 | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter |
Sigma-Aldrich
m.cnreagent.com
