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Anti-EHMT1/GLP1 Antibody

品牌
Sigma-Aldrich
货号
09-078
规格纯度
Upstate®, from rabbit
参考价格
6526.19 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-EHMT1/GLP1 Antibody
G9a like protein, H3-K9-HMTase, Histone H3-K9 methyltransferase, Histone-lysine N-methyltransferase, H3 lysine-9 specific, EC 2.1.1.43, euchromatic histone methyltransferase 1, euchromatic histone-lysine N-methyltransferase 1, Eu-HMTase1, FLJ12879 1, FP1
产品介绍:

产品说明

一般描述

G9a-Like Protein 1 (GLP1), also known as Euchromatic histone lysine N-methyl-transferase 1 (EMHT1), is a histone methyltransferase that methylates Lys9 of histone H3. H3Lys9 methylation is a marker for epigenetic transcriptional repression. EMHT1/GLP1 is targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it contributes to silencing of Myc- and E2F-responsive genes, suggesting a role in G0/G1 transition in cell cycle. EMHT1/GLP1 is phosphorylated upon DNA damage, probably by ATM or ATR. Defects in EHMT1 result in severe mental retardation, hypotonia, and epileptic seizures.

特异性

Recognizes EMHT1/GLP1

免疫原

KLH conjugated synthetic peptide (KHTQDSARVNPQDGTNTLTR(C) corresponding to a.a. 40-59 of human EMHT1/GLP1.
Epitope: a.a. 40-59

应用

Research Sub Category
Chromatin Biology

Histones
Research Category
Epigenetics & Nuclear Function
Use Anti-EHMT1/GLP1 Antibody (Rabbit Polyclonal Antibody) validated in WB to detect EHMT1/GLP1 also known as H3-K9-HMTase 5, Histone H3-K9 methyltransferase 5.

质量

Routinely evaluated by immunoblot.

目标描述

160 kda

外形

Immunoaffinity purified rabbit IgG in PBS containing 0.1% sodium azide, 30% glycerol
ImmunoAffinity Purified

储存及稳定性

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

生物来源rabbit
质量水平100
抗体形式affinity purified immunoglobulin
antibody product typeprimary antibodies
克隆polyclonal
纯化方式affinity chromatography
species reactivityhuman
manufacturer/tradenameUpstate®
technique(s)western blot: suitable
同位素/亚型IgG
NCBI登记号NM_012117.1
UniProt登记号Q9H9B1
运输wet ice
Gene Informationhuman ... EHMT1(79813)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 2

Sigma-Aldrich

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