产品说明
一般描述
Chemical structure: sulfonamide
应用
Sulfacetamide is an antibiotic that is used to treat skin infections and urinary tract infections. Sulfacetamide is used to study the treatment of acne and seborrheic dermatitis. It is used to study neonatal chlamydial conjunctivitis and meningococcal conjunctivitis.
生化/生理作用
Sulfacetamide is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It is active against Gram positive bacteria, Gram negative bacteria and Chlamydia. Mode of resistance is via the alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.
包装
100G,500G
其他说明
Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place.Storage class (TRGS 510): Non Combustible Solids
基本信息
经验(实验)分子式 | C8H10N2O3S |
分子量 | 214.24 |
Beilstein | 981718 |
EC 号 | 205-640-6 |
MDL编号 | MFCD00066501 |
PubChem化学物质编号 | 24899803 |
NACRES | NA.85 |
产品性质
质量水平 | 200 |
测定 | ≥98.0% |
作用机制 | DNA synthesis | interferes |
抗生素抗菌谱 | Gram-negative bacteria Gram-positive bacteria mycoplasma |
SMILES string | CC(=O)NS(=O)(=O)c1ccc(N)cc1 |
InChI | 1S/C8H10N2O3S/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8/h2-5H,9H2,1H3,(H,10,11) |
InChI key | SKIVFJLNDNKQPD-UHFFFAOYSA-N |
Sigma-Aldrich