产品说明
包装
10, 50 mg in glass bottle
生化/生理作用
Dorzolamide is a potent carbonic anhydrase II inhibitor with an IC50 value of 0.16 nM on human erythrocyte carbonic anhydrase II in vitro. It has been found to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension.
基本信息
经验(实验)分子式 | C10H16N2O4S3 |
分子量 | 324.44 |
MDL编号 | MFCD00865636 |
PubChem化学物质编号 | 329824746 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
旋光性 | [α]/D -25 to -35°, c = 1 in methanol |
颜色 | white to beige |
溶解性 | DMSO: 5 mg/mL (clear solution, warmed) |
储存温度 | room temp |
SMILES string | CCN[C@H]1C[C@H](C)S(=O)(=O)c2sc(cc12)S(N)(=O)=O |
InChI | 1S/C10H16N2O4S3/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16/h5-6,8,12H,3-4H2,1-2H3,(H2,11,15,16)/t6-,8-/m0/s1 |
InChI key | IAVUPMFITXYVAF-XPUUQOCRSA-N |
Gene Information | human ... CA2(760) |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 |
预防措施声明 | P264 - P270 - P301 + P312 - P501 |
危险分类 | Acute Tox. 4 Oral |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich