产品说明
应用
Rabeprazole sodium has been used as a proton pump inhibitor (PPI) to study its effects on spontaneous uterine contractile activity in pregnant women.
包装
10, 50 mg in glass bottle
生化/生理作用
Rabeprazole sodium is gastric proton pump inhibitor. It suppresses the production of acid in the stomach by inhibiting the gastric H+/K+ATPase (hydrogen-potassium adenosine triphosphatase) at the secretory surface of the gastric parietal cell. Rabeprazole sodium has been used clinically to treat acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, and prevent gastroinetestinal bleeds associated with NSAID use.
基本信息
经验(实验)分子式 | C18H20N3O3S · Na |
分子量 | 381.42 |
PubChem化学物质编号 | 329825431 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
储存条件 | desiccated |
颜色 | white to beige |
溶解性 | H2O: 10 mg/mL (clear solution) |
运输 | wet ice |
储存温度 | −20℃ |
SMILES string | [Na+].COCCCOc1ccnc(CS(=O)c2nc3ccccc3[n-]2)c1C |
InChI | 1S/C18H20N3O3S.Na/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18;/h3-4,6-9H,5,10-12H2,1-2H3;/q-1;+1 |
InChI key | KRCQSTCYZUOBHN-UHFFFAOYSA-N |
Gene Information | human ... ATP4A(495), ATP4B(496) |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 - H413 |
预防措施声明 | P264 - P270 - P273 - P301 + P312 - P501 |
危险分类 | Acute Tox. 4 Oral - Aquatic Chronic 4 |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich