产品说明
应用
Cirazoline hydrochloride has been used to activate the α1-noradrenergic receptors and to study the inhibitory effect of neurokinin1 (NK1) antagonists on respiratory activity using the brainstem transverse slice.
包装
10 mg in poly bottle
生化/生理作用
Cirazoline is a selective α1-adrenoceptor agonist and also a non-selective ligand for the imidazoline binding site. Cirazoline dereases spatial working memory performance in aged monkeys.
特点和优势
This compound is featured on the α1-Adrenoceptors and Imidazoline Binding Sites pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
基本信息
经验(实验)分子式 | C13H16N2O · HCl |
分子量 | 252.74 |
EC 号 | 254-995-3 |
MDL编号 | MFCD00274034 |
PubChem化学物质编号 | 24277770 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
形式 | solid |
颜色 | white |
溶解性 | H2O: >35 mg/mL |
SMILES string | Cl[H].C1CN=C(COc2ccccc2C3CC3)N1 |
InChI | 1S/C13H16N2O.ClH/c1-2-4-12(11(3-1)10-5-6-10)16-9-13-14-7-8-15-13;/h1-4,10H,5-9H2,(H,14,15);1H |
InChI key | XFRXWLWUUDJHPB-UHFFFAOYSA-N |
Gene Information | human ... ADRA1A(148), ADRA1B(147), ADRA1D(146) |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich